ISG20 Antibody

Product Specifications

Background

Exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. Degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. Involved in the antiviral function of IFN against RNA viruses.

NCBI Gene ID

3669

Swiss Prot

Q96AZ6

Accession Number

Q96AZ6

Host

Rabbit

Reactivity

Human

Immunogen

This ISG20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the Central region of human ISG20.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

20 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ISG20

NCBI Official Name

Interferon-stimulated gene 20 kDa protein

NCBI Organism

Homo sapiens

Background Reference 01

Hao, Y., et al. J. Huazhong Univ. Sci. Technol. Med. Sci. 28 (1) :11-13 (2008)

Background Reference 02

Horio, T., et al. FEBS Lett. 577 (1-2), 111-116 (2004) :

Background Reference 03

Espert, L., et al. J. Biol. Chem. 278 (18) :16151-16158 (2003)

Background Reference 04

Izmailova, E., et al. Nat. Med. 9 (2) :191-197 (2003)

Other Product Names

Interferon-stimulated gene 20 kDa protein, Estrogen-regulated transcript 45 protein, Promyelocytic leukemia nuclear body-associated protein ISG20, ISG20, HEM45