SDCBP2 Antibody
Product Specifications
Background
Syntenin 2 binds to the cytoplasmic domains of the syndecans: it contains a tandem repeat of PDZ domains that reacts with the FYA (phe-tyr-ala) C-terminal amino acid sequence of the syndecans. Cells that overexpress the fusion protein show numerous cell surface extensions, suggesting that Syntenin 2 may have an effect on cytoskeleton-membrane organization. Therefore, Syntenin 2 may function as an adaptor that couples syndecans to cytoskeletal proteins or cytosolic downstream signal-effectors.
NCBI Gene ID
27111
Swiss Prot
Q9H190
Accession Number
Q9H190
Host
Rabbit
Reactivity
Human
Immunogen
This SDCBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-127 amino acids from the N-terminal region of human SDCBP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
32 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SDCBP2
NCBI Official Name
Syntenin-2
NCBI Organism
Homo sapiens
Background Reference 01
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345 (3) :1022-1032 (2006)
Background Reference 02
Deloukas, P., et al. Nature 414 (6866) :865-871 (2001)
Background Reference 03
Koroll, M., et al. J. Biol. Chem. 276 (14) :10646-10654 (2001)
Background Reference 04
Borrell-Pages, M., et al. Mol. Biol. Cell 11 (12) :4217-4225 (2000)
Other Product Names
Syntenin-2, Syndecan-binding protein 2, SDCBP2, SITAC18
Tested Applications
WB
Protein ID
20455288
Physical Properties
Liquid
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