PPP1R9B Antibody

Product Specifications

Background

Spinophilin is a regulatory subunit of protein phosphatase-1 catalytic subunit (PP1; see MIM 176875) and is highly enriched in dendritic spines, specialized protrusions from dendritic shafts that receive most of the excitatory input in the central nervous system (Allen et al., 1997 [PubMed 9275233]) .

NCBI Gene ID

84687

Swiss Prot

Q96SB3

Accession Number

Q96SB3

Host

Rabbit

Reactivity

Human

Immunogen

This PPP1R9B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of human PPP1R9B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

89 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PPP1R9B

NCBI Official Name

Neurabin-2

NCBI Organism

Homo sapiens

Background Reference 01

Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :

Background Reference 02

Rajagopal, S., et al. J. Biol. Chem. 285 (23) :18060-18071 (2010)

Background Reference 03

Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259 (3) :151-163 (2009)

Background Reference 04

Sagara, M., et al. Oncogene 28 (10) :1357-1365 (2009)

Other Product Names

Neurabin-2, Neurabin-II, Protein phosphatase 1 regulatory subunit 9B, Spinophilin, PPP1R9B, PPP1R6

Tested Applications

Protein ID

90101416

Physical Properties

Liquid

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