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RAD52 Antibody

Product Specifications

Background

The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair.

NCBI Gene ID

5893

Swiss Prot

P43351

Accession Number

P43351

Host

Rabbit

Reactivity

Human

Immunogen

This RAD52 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-205 amino acids from the Central region of human RAD52.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

46 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RAD52

NCBI Official Name

DNA repair protein RAD52 homolog

NCBI Organism

Homo sapiens

Background Reference 01

Liu, Y., et al. Carcinogenesis 31 (10) :1762-1769 (2010)

Background Reference 02

Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press :

Background Reference 03

Briggs, F.B., et al. Am. J. Epidemiol. 172 (2) :217-224 (2010)

Background Reference 04

Liu, C.Y., et al. Carcinogenesis 31 (7) :1259-1263 (2010)

Other Product Names

DNA repair protein RAD52 homolog, RAD52

Tested Applications

WB

Protein ID

1172823

Physical Properties

Liquid

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