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DEF6 Antibody

Product Specifications

Background

DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 [PubMed 12923183]) .

NCBI Gene ID

50619

Swiss Prot

Q9H4E7

Accession Number

Q9H4E7

Host

Rabbit

Reactivity

Human

Immunogen

This DEF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 500-528 amino acids from the C-terminal region of human DEF6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

74 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

DEF6

NCBI Official Name

Differentially expressed in FDCP 6 homolog

NCBI Organism

Homo sapiens

Background Reference 01

Han, S., et al. Hum. Immunol. 71 (7) :727-730 (2010)

Background Reference 02

Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19 (5) :1356-1361 (2010)

Background Reference 03

Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :

Background Reference 04

Zhang, Z., et al. Cancer Epidemiol 33 (2) :130-136 (2009)

Other Product Names

Differentially expressed in FDCP 6 homolog, DEF-6, IRF4-binding protein, DEF6, IBP

Tested Applications

WB

Protein ID

74761430

Physical Properties

Liquid

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