TAS1R1 Antibody

Product Specifications

Background

The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

80835

Swiss Prot

Q7RTX1

Accession Number

Q7RTX1

Host

Rabbit

Reactivity

Human

Immunogen

This TAS1R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-351 amino acids from the Central region of human TAS1R1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

93 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TAS1R1

NCBI Official Name

Taste receptor type 1 member 1

NCBI Organism

Homo sapiens

Background Reference 01

Fushan, A.A., et al. Chem. Senses 35 (7) :579-592 (2010)

Background Reference 02

Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :

Background Reference 03

Prezeau, L., et al. Curr Opin Pharmacol 10 (1) :6-13 (2010)

Background Reference 04

Chandrashekar, J., et al. Nature 444 (7117) :288-294 (2006)

Other Product Names

Taste receptor type 1 member 1, G-protein coupled receptor 70, TAS1R1, GPR70, T1R1, TR1

Tested Applications

Protein ID

57013075

Physical Properties

Liquid

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