HSD17B1 Antibody

Product Specifications

Background

Favors the reduction of estrogens and androgens. Also has 20-alpha-HSD activity. Uses preferentially NADH.

NCBI Gene ID

3292

Swiss Prot

P14061

Accession Number

P14061

Host

Rabbit

Reactivity

Human

Immunogen

This HSD17B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-256 amino acids from the C-terminal region of human HSD17B1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HSD17B1

NCBI Official Name

Estradiol 17-beta-dehydrogenase 1

NCBI Organism

Homo sapiens

Background Reference 01

Canzian, F., et al. Hum. Mol. Genet. 19 (19) :3873-3884 (2010)

Background Reference 02

Liu, C.Y., et al. Carcinogenesis 31 (7) :1259-1263 (2010)

Background Reference 03

Lamp, M., et al. Gynecol. Endocrinol. (2010) In press :

Background Reference 04

Haller, F., et al. J. Mol. Biol. 399 (2) :255-267 (2010)

Other Product Names

Estradiol 17-beta-dehydrogenase 1, 17-beta-hydroxysteroid dehydrogenase type 1, 17-beta-HSD 1, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, E2DH, Placental 17-beta-hydroxysteroid dehydrogenase, HSD17B1, E17KSR, EDH17B1, EDH17B2, EDHB17