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MTMR6 Antibody

Product Specifications

Background

Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol-3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells.

NCBI Gene ID

9107

Swiss Prot

Q9Y217

Accession Number

Q9Y217

Host

Rabbit

Reactivity

Human

Immunogen

This MTMR6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-143 amino acids from the N-terminal region of human MTMR6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-558

Calculated Molecular Weight

72 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MTMR6

NCBI Official Name

Myotubularin-related protein 6

NCBI Organism

Homo sapiens

Background Reference 01

Zou, J., et al. J. Biol. Chem. 284 (4) :2064-2071 (2009)

Background Reference 02

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 03

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 04

Srivastava, S., et al. Mol. Cell. Biol. 26 (15) :5595-5602 (2006)

Other Product Names

Myotubularin-related protein 6, 313-, MTMR6

Tested Applications

WB

Protein ID

317373414

Physical Properties

Liquid

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