MTMR6 Antibody
Product Specifications
Background
Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol-3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells.
NCBI Gene ID
9107
Swiss Prot
Q9Y217
Accession Number
Q9Y217
Host
Rabbit
Reactivity
Human
Immunogen
This MTMR6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-143 amino acids from the N-terminal region of human MTMR6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
72 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MTMR6
NCBI Official Name
Myotubularin-related protein 6
NCBI Organism
Homo sapiens
Background Reference 01
Zou, J., et al. J. Biol. Chem. 284 (4) :2064-2071 (2009)
Background Reference 02
Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)
Background Reference 03
Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)
Background Reference 04
Srivastava, S., et al. Mol. Cell. Biol. 26 (15) :5595-5602 (2006)
Other Product Names
Myotubularin-related protein 6, 313-, MTMR6
Tested Applications
WB
Protein ID
317373414
Physical Properties
Liquid
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