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DND1 Antibody

Product Specifications

Background

This gene encodes a protein that binds to microRNA-targeting sequences of mRNAs, inhibiting microRNA-mediated repression. Reduced expression of this gene has been implicated in tongue squamous cell carcinoma. Two pseudogenes of this gene are located on the long arm of chromosome 17.

NCBI Gene ID

373863

Swiss Prot

Q8IYX4

Accession Number

Q8IYX4

Host

Rabbit

Reactivity

Human

Immunogen

This DND1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the Central region of human DND1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

39 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

DND1

NCBI Official Name

Dead end protein homolog 1

NCBI Organism

Homo sapiens

Background Reference 01

Liu, X., et al. FEBS Lett. 584 (18) :4115-4120 (2010)

Background Reference 02

Sijmons, R.H., et al. Fam. Cancer 9 (3) :439-442 (2010)

Background Reference 03

Kedde, M., et al. Cell Cycle 7 (7) :899-903 (2008)

Background Reference 04

Linger, R., et al. Genes Chromosomes Cancer 47 (3) :247-252 (2008)

Other Product Names

Dead end protein homolog 1, RNA-binding motif, single-stranded-interacting protein 4, DND1, RBMS4

Tested Applications

WB

Protein ID

60389799

Physical Properties

Liquid

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