ACCN4 Antibody

Product Specifications

Background

This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. Alternative splicing at this locus results in two transcript variants encoding different isoforms.

NCBI Gene ID

55515

Swiss Prot

Q96FT7

Accession Number

Q96FT7

Host

Rabbit

Reactivity

Human

Immunogen

This ACCN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-52 amino acids from the N-terminal region of human ACCN4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

70 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ASIC4

NCBI Official Name

Acid-sensing ion channel 4

NCBI Organism

Homo sapiens

Background Reference 01

Donier, E., et al. Eur. J. Neurosci. 28 (1) :74-86 (2008)

Background Reference 02

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Background Reference 03

Hillier, L.W., et al. Nature 434 (7034) :724-731 (2005)

Background Reference 04

Grunder, S., et al. Eur. J. Hum. Genet. 9 (9) :672-676 (2001)

Other Product Names

Acid-sensing ion channel 4, ASIC4, Amiloride-sensitive cation channel 4, Amiloride-sensitive cation channel 4, pituitary, ASIC4, ACCN4

Tested Applications

Protein ID

296434387

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

A17063-10mM-D 10 mM x 1mL in DMSO

MK-3903 10mM * 1mL in DMSO

Ask

View Details

MBS1067365-01 0.05 mg (E-Coli)

Recombinant Buchnera aphidicola subsp. Acyrthosiphon pisum Probable peroxiredoxin (BU182)

Ask

View Details

MBS1067365-02 0.05 mg (Yeast)

Recombinant Buchnera aphidicola subsp. Acyrthosiphon pisum Probable peroxiredoxin (BU182)

Ask

View Details

MBS1067365-03 0.2 mg (E-Coli)

Recombinant Buchnera aphidicola subsp. Acyrthosiphon pisum Probable peroxiredoxin (BU182)

Ask

View Details

MBS1067365-04 0.5 mg (E-Coli)

Recombinant Buchnera aphidicola subsp. Acyrthosiphon pisum Probable peroxiredoxin (BU182)

Ask

View Details

MBS1067365-05 0.05 mg (Baculovirus)

Recombinant Buchnera aphidicola subsp. Acyrthosiphon pisum Probable peroxiredoxin (BU182)

Ask

View Details