PHF21A Antibody

Product Specifications

Background

The PHF21A gene encodes BHC80, a component of a BRAF35 (MIM 605535) /histone deacetylase (HDAC; see MIM 601241) complex (BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressor element-1 (RE1) or neural restrictive silencer (NRS) (Hakimi et al., 2002 [PubMed 12032298]) .

NCBI Gene ID

51317

Swiss Prot

Q96BD5

Accession Number

Q96BD5

Host

Rabbit

Reactivity

Human

Immunogen

This PHF21A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 436-464 amino acids from the Central region of human PHF21A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

75 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PHF21A

NCBI Official Name

PHD finger protein 21A

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Klajn, A., et al. J. Neurosci. 29 (19) :6296-6307 (2009)

Background Reference 03

Hailesellasse Sene, K., et al. BMC Genomics 8, 85 (2007) :

Background Reference 04

Shi, Y.J., et al. Mol. Cell 19 (6) :857-864 (2005)

Other Product Names

PHD finger protein 21A, BHC80a, BRAF35-HDAC complex protein BHC80, PHF21A, BHC80, KIAA1696

Tested Applications

Protein ID

74731224

Physical Properties

Liquid

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