ADAM23 Antibody

Product Specifications

Background

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is highly expressed in the brain and may function as an integrin ligand in the brain.

NCBI Gene ID

8745

Swiss Prot

O75077

Accession Number

O75077

Host

Rabbit

Reactivity

Human

Immunogen

This ADAM23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 803-831 amino acids from the C-terminal region of human ADAM23.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

92 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ADAM23

NCBI Official Name

Disintegrin and metalloproteinase domain-containing protein 23

NCBI Organism

Homo sapiens

Background Reference 01

Pan, Q., et al. Biochem. Biophys. Res. Commun. 401 (2) :306-312 (2010)

Background Reference 02

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 03

Ferreira, M.A., et al. Allergy 64 (11) :1623-1628 (2009)

Background Reference 04

Costa, M.D., et al. Neurosci. Lett. 461 (1) :16-20 (2009)

Other Product Names

Disintegrin and metalloproteinase domain-containing protein 23, ADAM 23, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3, MDC-3, ADAM23, MDC3