FOSL2 Antibody
Product Specifications
Background
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
NCBI Gene ID
2355
Swiss Prot
P15408
Accession Number
P15408
Host
Rabbit
Reactivity
Human
Immunogen
This FOSL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-248 amino acids from the C-terminal region of human FOSL2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
35 kDa
Fragment
Rabbit Ig
Symbol
FOSL2
NCBI Official Name
Fos-related antigen 2
NCBI Organism
Homo sapiens
Background Reference 01
Bozec, A., et al. J. Cell Biol. 190 (6) :1093-1106 (2010)
Background Reference 02
Bolat, I., et al. Folia Histochem. Cytobiol. 48 (2) :197-201 (2010)
Background Reference 03
Reich, N., et al. Arthritis Rheum. 62 (1) :280-290 (2010)
Background Reference 04
Maurer, B., et al. Circulation 120 (23) :2367-2376 (2009)
Other Product Names
Fos-related antigen 2, FRA-2, FOSL2, FRA2
Tested Applications
WB, IF
Protein ID
120487
Physical Properties
Liquid
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