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KLF12 Antibody

Product Specifications

Background

Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

NCBI Gene ID

11278

Swiss Prot

Q9Y4X4

Accession Number

Q9Y4X4

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This KLF12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-312 amino acids from the C-terminal region of human KLF12.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-515

Calculated Molecular Weight

44 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

KLF12

NCBI Official Name

Krueppel-like factor 12

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Eyre, S., et al. Ann. Rheum. Dis. 69 (7) :1407-1408 (2010)

Background Reference 03

Wieczorek, S., et al. J. Mol. Med. 88 (4) :413-421 (2010)

Background Reference 04

Petersen, G.M., et al. Nat. Genet. 42 (3) :224-228 (2010)

Other Product Names

Krueppel-like factor 12, Transcriptional repressor AP-2rep, KLF12, AP2REP

Tested Applications

WB

Protein ID

91771555

Physical Properties

Liquid

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