ELK3 Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present.
NCBI Gene ID
2004
Swiss Prot
P41970
Accession Number
P41970
Host
Rabbit
Reactivity
Human
Immunogen
This ELK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the N-terminal region of human ELK3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=58-514
Calculated Molecular Weight
44 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ELK3
NCBI Official Name
ETS domain-containing protein Elk-3
NCBI Organism
Homo sapiens
Background Reference 01
Serchov, T., et al. J. Biol. Chem. 285 (28) :21223-21232 (2010)
Background Reference 02
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 03
Li, B., et al. Tohoku J. Exp. Med. 216 (2) :139-147 (2008)
Background Reference 04
Wasylyk, C., et al. Cancer Res. 68 (5) :1275-1283 (2008)
Other Product Names
ETS domain-containing protein Elk-3, ETS-related protein ERP, ETS-related protein NET, Serum response factor accessory protein 2, SAP-2, SRF accessory protein 2, ELK3, NET, SAP2
Tested Applications
WB
Protein ID
116241349
Physical Properties
Liquid
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