ZW10 Antibody
Product Specifications
Background
This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. The encoded protein binds to centromeres during the prophase, metaphase, and early anaphase cell division stages and to kinetochore microtubules during metaphase.
NCBI Gene ID
9183
Swiss Prot
O43264
Accession Number
O43264
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This ZW10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-88 amino acids from the N-terminal region of human ZW10.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
89 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ZW10
NCBI Official Name
Centromere/kinetochore protein zw10 homolog
NCBI Organism
Homo sapiens
Background Reference 01
Chan, Y.W., et al. J. Cell Biol. 185 (5) :859-874 (2009)
Background Reference 02
Aoki, T., et al. Mol. Biol. Cell 20 (11) :2639-2649 (2009)
Background Reference 03
Inoue, M., et al. Genes Cells 13 (8) :905-914 (2008)
Background Reference 04
Famulski, J.K., et al. J. Cell Biol. 180 (3) :507-520 (2008)
Other Product Names
Centromere/kinetochore protein zw10 homolog, ZW10
Tested Applications
WB
Physical Properties
Liquid
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