CNTROB Antibody
Product Specifications
Background
CNTROB is a centrosomal protein that interacts with BRCA2 (MIM 600185) and is required for centriole duplication and cytokinesis (Zou et al., 2005 [PubMed 16275750]) .[supplied by OMIM].
NCBI Gene ID
116840
Swiss Prot
Q8N137
Accession Number
Q8N137
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This CNTROB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-430 amino acids from the Central region of human CNTROB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
101 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CNTROB
NCBI Official Name
Centrobin
NCBI Organism
Homo sapiens
Background Reference 01
Lee, J., et al. J. Biol. Chem. 285 (33) :25476-25484 (2010)
Background Reference 02
Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
Background Reference 03
Jeffery, J.M., et al. Oncogene 29 (18) :2649-2658 (2010)
Background Reference 04
Song, L., et al. Cell. Signal. 22 (5) :857-864 (2010)
Other Product Names
Centrobin, Centrosomal BRCA2-interacting protein, LYST-interacting protein 8, CNTROB, LIP8
Tested Applications
WB
Protein ID
74728485
Physical Properties
Liquid
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