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CNTROB Antibody

Product Specifications

Background

CNTROB is a centrosomal protein that interacts with BRCA2 (MIM 600185) and is required for centriole duplication and cytokinesis (Zou et al., 2005 [PubMed 16275750]) .[supplied by OMIM].

NCBI Gene ID

116840

Swiss Prot

Q8N137

Accession Number

Q8N137

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This CNTROB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-430 amino acids from the Central region of human CNTROB.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-510

Calculated Molecular Weight

101 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CNTROB

NCBI Official Name

Centrobin

NCBI Organism

Homo sapiens

Background Reference 01

Lee, J., et al. J. Biol. Chem. 285 (33) :25476-25484 (2010)

Background Reference 02

Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :

Background Reference 03

Jeffery, J.M., et al. Oncogene 29 (18) :2649-2658 (2010)

Background Reference 04

Song, L., et al. Cell. Signal. 22 (5) :857-864 (2010)

Other Product Names

Centrobin, Centrosomal BRCA2-interacting protein, LYST-interacting protein 8, CNTROB, LIP8

Tested Applications

WB

Protein ID

74728485

Physical Properties

Liquid

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