RAD52 Antibody
Product Specifications
Background
The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair.
NCBI Gene ID
5893
Swiss Prot
P43351
Accession Number
P43351
Host
Rabbit
Reactivity
Human
Immunogen
This RAD52 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-416 amino acids from the C-terminal region of human RAD52.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
46 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RAD52
NCBI Official Name
DNA repair protein RAD52 homolog
NCBI Organism
Homo sapiens
Background Reference 01
Liu, Y., et al. Carcinogenesis 31 (10) :1762-1769 (2010)
Background Reference 02
Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press :
Background Reference 03
Briggs, F.B., et al. Am. J. Epidemiol. 172 (2) :217-224 (2010)
Background Reference 04
Liu, C.Y., et al. Carcinogenesis 31 (7) :1259-1263 (2010)
Other Product Names
DNA repair protein RAD52 homolog, RAD52
Tested Applications
WB
Protein ID
1172823
Physical Properties
Liquid
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