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BAG5 Antibody

Product Specifications

Background

BAG5 is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene.

NCBI Gene ID

9529

Swiss Prot

Q9UL15

Accession Number

Q9UL15

Host

Rabbit

Reactivity

Human

Immunogen

This BAG5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human BAG5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Obesity

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-481

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

BAG5

NCBI Official Name

BAG family molecular chaperone regulator 5

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care (2010) In press :

Background Reference 02

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Background Reference 03

Kalia, S.K., et al. Neuron 44 (6) :931-945 (2004)

Background Reference 04

Takayama, S., et al. J. Biol. Chem. 274 (2) :781-786 (1999)

Other Product Names

BAG family molecular chaperone regulator 5, BAG-5, Bcl-2-associated athanogene 5, BAG5, KIAA0873

Tested Applications

WB

Protein ID

12643895

Physical Properties

Liquid

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