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PKD2L1 Antibody

Product Specifications

Background

PKD2L1 is a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Alternative splice variants have been described but their full length sequences have not been determined.

NCBI Gene ID

9033

Swiss Prot

Q9P0L9

Accession Number

Q9P0L9

Host

Rabbit

Reactivity

Human

Immunogen

This PKD2L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human PKD2L1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

92 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PKD2L1

NCBI Official Name

Polycystic kidney disease 2-like 1 protein

NCBI Organism

Homo sapiens

Background Reference 01

Molland, K.L., et al. Biochem. J. 429 (1) :171-183 (2010)

Background Reference 02

Kawaguchi, H., et al. J. Biol. Chem. 285 (23) :17277-17281 (2010)

Background Reference 03

Li, Q., et al. J. Neurochem. 103 (6) :2391-2400 (2007)

Background Reference 04

Geng, L., et al. J. Cell. Sci. 119 (PT 7), 1383-1395 (2006) :

Other Product Names

Polycystic kidney disease 2-like 1 protein, Polycystin-2 homolog, Polycystin-2L1, Polycystin-L, Polycystin-L1, PKD2L1, PKD2L, PKDL, TRPP3

Tested Applications

WB

Protein ID

23821938

Physical Properties

Liquid

Curated Selection

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