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RGS8 Antibody

Product Specifications

Background

RGS8 is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation.

NCBI Gene ID

85397

Swiss Prot

P57771

Accession Number

P57771

Host

Rabbit

Reactivity

Human

Immunogen

This RGS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human RGS8.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

21 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RGS8

NCBI Official Name

Regulator of G-protein signaling 8

NCBI Organism

Homo sapiens

Background Reference 01

Wang, J., et al. Carcinogenesis 31 (10) :1755-1761 (2010)

Background Reference 02

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 03

Fujii, S., et al. Biochem. Biophys. Res. Commun. 377 (1) :200-204 (2008)

Background Reference 04

Campbell, D.B., et al. Schizophr. Res. 101 (1-3), 67-75 (2008) :

Other Product Names

Regulator of G-protein signaling 8, RGS8, RGS8

Tested Applications

WB

Protein ID

13124465

Physical Properties

Liquid

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