NFS1 Antibody

Product Specifications

Background

Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described.

NCBI Gene ID

9054

Swiss Prot

Q9Y697

Accession Number

Q9Y697

Host

Rabbit

Reactivity

Human

Immunogen

This NFS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-149 amino acids from the Central region of human NFS1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

50 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NFS1

NCBI Official Name

Cysteine desulfurase, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Naamati, A., et al. J. Biol. Chem. 284 (44) :30200-30208 (2009)

Background Reference 02

Marelja, Z., et al. J. Biol. Chem. 283 (37) :25178-25185 (2008)

Background Reference 03

Wu, C., et al. Proteomics 7 (11) :1775-1785 (2007)

Background Reference 04

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Other Product Names

Cysteine desulfurase, mitochondrial, NFS1, NIFS

Tested Applications

Protein ID

62512153

Physical Properties

Liquid

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