COL6A2 Antibody

Product Specifications

Background

COL6A2 is one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene. [provided by RefSeq].

NCBI Gene ID

1292

Swiss Prot

P12110

Accession Number

P12110

Host

Rabbit

Reactivity

Human

Immunogen

This COL6A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 719-747 amino acids from the C-terminal region of human COL6A2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

109 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

COL6A2

NCBI Official Name

Collagen alpha-2 (VI) chain

NCBI Organism

Homo sapiens

Background Reference 01

Zhang, R.Z., et al. J. Biol. Chem. 285 (13) :10005-10015 (2010)

Background Reference 02

Bovolenta, M., et al. BMC Med. Genet. 11, 44 (2010) :

Background Reference 03

Chapuis, J., et al. Mol. Psychiatry 14 (11) :1004-1016 (2009)

Background Reference 04

Freise, C., et al. Matrix Biol. 28 (8) :480-489 (2009)

Other Product Names

Collagen alpha-2 (VI) chain, COL6A2

Tested Applications

Protein ID

125987812

Physical Properties

Liquid

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