COL6A2 Antibody
Product Specifications
Background
COL6A2 is one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene. [provided by RefSeq].
NCBI Gene ID
1292
Swiss Prot
P12110
Accession Number
P12110
Host
Rabbit
Reactivity
Human
Immunogen
This COL6A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 719-747 amino acids from the C-terminal region of human COL6A2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
109 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
COL6A2
NCBI Official Name
Collagen alpha-2 (VI) chain
NCBI Organism
Homo sapiens
Background Reference 01
Zhang, R.Z., et al. J. Biol. Chem. 285 (13) :10005-10015 (2010)
Background Reference 02
Bovolenta, M., et al. BMC Med. Genet. 11, 44 (2010) :
Background Reference 03
Chapuis, J., et al. Mol. Psychiatry 14 (11) :1004-1016 (2009)
Background Reference 04
Freise, C., et al. Matrix Biol. 28 (8) :480-489 (2009)
Other Product Names
Collagen alpha-2 (VI) chain, COL6A2
Tested Applications
WB
Protein ID
125987812
Physical Properties
Liquid
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