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SLC24A3 Antibody

Product Specifications

Background

Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001 [PubMed 11294880]) .

NCBI Gene ID

57419

Swiss Prot

Q9HC58

Accession Number

Q9HC58

Host

Rabbit

Reactivity

Human

Immunogen

This SLC24A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-108 amino acids from the N-terminal region of human SLC24A3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-449

Calculated Molecular Weight

72 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SLC24A3

NCBI Official Name

Sodium/potassium/calcium exchanger 3

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Cheng, Y.C., et al. Circ Cardiovasc Genet 2 (4) :329-337 (2009)

Background Reference 03

Deloukas, P., et al. Nature 414 (6866) :865-871 (2001)

Background Reference 04

Kraev, A., et al. J. Biol. Chem. 276 (25) :23161-23172 (2001)

Other Product Names

Sodium/potassium/calcium exchanger 3, Na (+) /K (+) /Ca (2+) -exchange protein 3, Solute carrier family 24 member 3, SLC24A3, NCKX3

Tested Applications

WB

Protein ID

116242671

Physical Properties

Liquid

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