CDCP1 Antibody
Product Specifications
Background
CDCP1 is a transmembrane protein containing three extracellular CUB domains. This protein is found to be overexpressed in colon and lung cancers. Its expression level is correlated with the metastatic ability of carcinoma cells. This protein is located on the cell surface. It has been shown to be tyrosine phosphorylated in a cancer cell line. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
NCBI Gene ID
64866
Swiss Prot
Q9H5V8
Accession Number
Q9H5V8
Host
Rabbit
Reactivity
Human
Immunogen
This CDCP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 704-732 amino acids from the C-terminal region of human CDCP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=58-436
Calculated Molecular Weight
93 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CDCP1
NCBI Official Name
CUB domain-containing protein 1
NCBI Organism
Homo sapiens
Background Reference 01
He, Y., et al. J. Biol. Chem. 285 (34) :26162-26173 (2010)
Background Reference 02
Miyazawa, Y., et al. Cancer Res. 70 (12) :5136-5146 (2010)
Background Reference 03
Mamat, S., et al. Oncol. Rep. 23 (5) :1221-1227 (2010)
Background Reference 04
Fukuchi, K., et al. Mol. Pharm. 7 (1) :245-253 (2010)
Other Product Names
CUB domain-containing protein 1, Membrane glycoprotein gp140, Subtractive immunization M plus HEp3-associated 135 kDa protein, SIMA135, Transmembrane and associated with src kinases, CD318, CDCP1, TRASK
Tested Applications
WB
Protein ID
317373455
Physical Properties
Liquid
Curated Selection
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