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POLD3 Antibody

Product Specifications

Background

The DNA polymerase delta complex is involved in DNA replication and repair, and it consists of the proliferating cell nuclear antigen (PCNA; MIM 176740), the multisubunit replication factor C (see MIM 102579), and the 4 subunit polymerase complex: POLD1 (MIM 174761), POLD2 (MIM 600815), POLD3, and POLD4 (MIM 611525) (Liu and Warbrick, 2006 [PubMed 16934752]) .[supplied by OMIM].

NCBI Gene ID

10714

Swiss Prot

Q15054

Accession Number

Q15054

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This POLD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 416-443 amino acids from the C-terminal region of human POLD3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-435

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

POLD3

NCBI Official Name

DNA polymerase delta subunit 3

NCBI Organism

Homo sapiens

Background Reference 01

Michiels, S., et al. Carcinogenesis 30 (5) :763-768 (2009)

Background Reference 02

Baranovskiy, A.G., et al. Cell Cycle 7 (19) :3026-3036 (2008)

Background Reference 03

Baranovskiy, A.G., et al. Acta Crystallogr. Sect.Struct. Biol. Cryst. Commun. 64 (PT 9), 822-824 (2008) :

Background Reference 04

Lemmens, L., et al. Biochem. Biophys. Res. Commun. 367 (2) :264-270 (2008)

Other Product Names

DNA polymerase delta subunit 3, DNA polymerase delta subunit p66, POLD3, KIAA0039

Tested Applications

WB

Protein ID

17375506

Physical Properties

Liquid

Curated Selection

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