ISL1 Antibody

Product Specifications

Background

ISL1 is a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.

NCBI Gene ID

3670

Swiss Prot

P61371

Accession Number

P61371

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ISL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the Central region of human ISL1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Zebrafish, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

39 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ISL1

NCBI Official Name

Insulin gene enhancer protein ISL-1

NCBI Organism

Homo sapiens

Background Reference 01

De Luca, A., et al. Clin. Genet. (2010) In press :

Background Reference 02

Davis, O.S., et al. Behav. Genet. (2010) In press :

Background Reference 03

Genead, R., et al. Stem Cell Res 4 (1) :69-76 (2010)

Background Reference 04

Stevens, K.N., et al. PLoS ONE (5), E10855 (2010) :

Other Product Names

Insulin gene enhancer protein ISL-1, Islet-1, ISL1

Tested Applications

Protein ID

47606423

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MK200102 1 Kit

Eaf2 Mouse qPCR Template Standard (NM_134111)

Ask

View Details

A43462-100UL 100 µL

PPP2R3C Antibody

Ask

View Details

470657 1 mL

Dengue Virus (DENV-Serotype 4)

Ask

View Details

48635021 500 ng

TSPYL5 Protein Vector (Human) (pPM-C-HA)

Ask

View Details

228383-01 250 mg

1- (2-Fluorophenyl) -5-methyl-1H-pyrazole-4-carboxylic acid 98+% (HPLC)

Ask

View Details

228383-02 1 g

1- (2-Fluorophenyl) -5-methyl-1H-pyrazole-4-carboxylic acid 98+% (HPLC)

Ask

View Details