BOLL Antibody
Product Specifications
Background
BOLL belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like) . Loss of this gene function results in the absence of sperm in semen (azoospermia) . Histological studies demonstrated that the primary defect is at the meiotic G2/M transition.
NCBI Gene ID
66037
Swiss Prot
Q8N9W6
Accession Number
Q8N9W6
Host
Rabbit
Reactivity
Human
Immunogen
This BOLL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-51 amino acids from the N-terminal region of human BOLL.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
31 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
BOLL
NCBI Official Name
Protein boule-like
NCBI Organism
Homo sapiens
Background Reference 01
Chen, P., et al. J. Androl. 31 (2) :163-168 (2010)
Background Reference 02
Kee, K., et al. Nature 462 (7270) :222-225 (2009)
Background Reference 03
Lin, Y.M., et al. J. Clin. Endocrinol. Metab. 94 (7) :2650-2657 (2009)
Background Reference 04
Bilguvar, K., et al. Nat. Genet. 40 (12) :1472-1477 (2008)
Other Product Names
Protein boule-like, BOLL, BOULE
Tested Applications
WB
Protein ID
44887719
Physical Properties
Liquid
Curated Selection
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