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BOLL Antibody

Product Specifications

Background

BOLL belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like) . Loss of this gene function results in the absence of sperm in semen (azoospermia) . Histological studies demonstrated that the primary defect is at the meiotic G2/M transition.

NCBI Gene ID

66037

Swiss Prot

Q8N9W6

Accession Number

Q8N9W6

Host

Rabbit

Reactivity

Human

Immunogen

This BOLL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-51 amino acids from the N-terminal region of human BOLL.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

31 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

BOLL

NCBI Official Name

Protein boule-like

NCBI Organism

Homo sapiens

Background Reference 01

Chen, P., et al. J. Androl. 31 (2) :163-168 (2010)

Background Reference 02

Kee, K., et al. Nature 462 (7270) :222-225 (2009)

Background Reference 03

Lin, Y.M., et al. J. Clin. Endocrinol. Metab. 94 (7) :2650-2657 (2009)

Background Reference 04

Bilguvar, K., et al. Nat. Genet. 40 (12) :1472-1477 (2008)

Other Product Names

Protein boule-like, BOLL, BOULE

Tested Applications

WB

Protein ID

44887719

Physical Properties

Liquid

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