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TMOD1 Antibody

Product Specifications

Background

TMOD1 is a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton. Multiple transcript variants encoding the same protein have been found for this gene.

NCBI Gene ID

7111

Swiss Prot

P28289

Accession Number

P28289

Host

Rabbit

Reactivity

Human

Immunogen

This TMOD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-198 amino acids from the Central region of human TMOD1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-406

Calculated Molecular Weight

41 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TMOD1

NCBI Official Name

Tropomodulin-1

NCBI Organism

Homo sapiens

Background Reference 01

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 02

Kong, K.Y., et al. J. Biol. Chem. 281 (14) :9589-9599 (2006)

Background Reference 03

Vera, C., et al. Arch. Biochem. Biophys. 444 (2) :130-138 (2005)

Background Reference 04

Pawlak, G., et al. Int. J. Cancer 110 (3) :368-373 (2004)

Other Product Names

Tropomodulin-1, Erythrocyte tropomodulin, E-Tmod, TMOD1, D9S57E, TMOD

Tested Applications

WB

Protein ID

135922

Physical Properties

Liquid

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