ELOVL4 Antibody

Product Specifications

Background

ELOVL4 is a membrane-bound protein which is a member of the ELO family, proteins which participate in the biosynthesis of fatty acids. Consistent with the expression of the encoded protein in photoreceptor cells of the retina, mutations and small deletions in this gene are associated with Stargardt-like macular dystrophy (STGD3) and autosomal dominant Stargardt-like macular dystrophy (ADMD), also referred to as autosomal dominant atrophic macular degeneration.

NCBI Gene ID

6785

Swiss Prot

Q9GZR5

Accession Number

Q9GZR5

Host

Rabbit

Reactivity

Human

Immunogen

This ELOVL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-314 amino acids from the C-terminal region of human ELOVL4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

37 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ELOVL4

NCBI Official Name

Elongation of very long chain fatty acids protein 4

NCBI Organism

Homo sapiens

Background Reference 01

Kasperaviciute, D., et al. Brain 133 (PT 7), 2136-2147 (2010) :

Background Reference 02

Vasireddy, V., et al. Prog Retin Eye Res 29 (3) :191-207 (2010)

Background Reference 03

Gu, H., et al. Zhonghua Yan Ke Za Zhi 46 (2) :125-128 (2010)

Background Reference 04

DeAngelis, M.M., et al. Arch. Ophthalmol. 125 (1) :49-54 (2007)

Other Product Names

Elongation of very long chain fatty acids protein 4, 3-keto acyl-CoA synthase ELOVL4, ELOVL fatty acid elongase 4, ELOVL FA elongase 4, Very-long-chain 3-oxoacyl-CoA synthase 4, ELOVL4