SMO Antibody
Product Specifications
Background
The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex.
NCBI Gene ID
6608
Swiss Prot
Q99835
Accession Number
Q99835
Host
Rabbit
Reactivity
Human
Immunogen
This SMO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 539-567 amino acids from the Central region of human SMO.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
86 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SMO
NCBI Official Name
Smoothened homolog
NCBI Organism
Homo sapiens
Background Reference 01
Zhang, L., et al. Oral Dis 16 (8) :818-822 (2010)
Background Reference 02
Desch, P., et al. Oncogene 29 (35) :4885-4895 (2010)
Background Reference 03
Walter, K., et al. Clin. Cancer Res. 16 (6) :1781-1789 (2010)
Background Reference 04
Hirotsu, M., et al. Mol. Cancer 9, (2010) :
Other Product Names
Smoothened homolog, SMO, Protein Gx, SMO, SMOH
Tested Applications
WB
Protein ID
6226142
Physical Properties
Liquid
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