HIST2H2BF Antibody
Product Specifications
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
NCBI Gene ID
440689
Swiss Prot
Q5QNW6
Accession Number
Q5QNW6
Host
Rabbit
Reactivity
Human
Immunogen
This HIST2H2BF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human HIST2H2BF.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Bovine, Pr
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
14 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HIST2H2BF
NCBI Official Name
Histone H2B type 2-F
NCBI Organism
Homo sapiens
Background Reference 01
Kim, S.C., et al. Mol. Cell 23 (4) :607-618 (2006)
Background Reference 02
Pavri, R., et al. Cell 125 (4) :703-717 (2006)
Background Reference 03
Bonenfant, D., et al. Mol. Cell Proteomics 5 (3) :541-552 (2006)
Background Reference 04
Zhu, B., et al. Mol. Cell 20 (4) :601-611 (2005)
Other Product Names
Histone H2B type 2-F, HIST2H2BF
Tested Applications
WB
Protein ID
74743113
Physical Properties
Liquid
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