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VSX1 Antibody

Product Specifications

Background

VSX1 contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus.

NCBI Gene ID

30813

Swiss Prot

Q9NZR4

Accession Number

Q9NZR4

Host

Rabbit

Reactivity

Human

Immunogen

This VSX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-154 amino acids from the Central region of human VSX1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

38 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

VSX1

NCBI Official Name

Visual system homeobox 1

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Dash, D.P., et al. Eye (Lond) 24 (6) :1085-1092 (2010)

Background Reference 03

Stabuc-Silih, M., et al. Cornea 29 (2) :172-176 (2010)

Background Reference 04

Stabuc-Silih, M., et al. Acta Dermatovenerol Alp Panonica Adriat 19 (2) :3-10 (2010)

Other Product Names

Visual system homeobox 1, Homeodomain protein RINX, Retinal inner nuclear layer homeobox protein, Transcription factor VSX1, VSX1, RINX

Tested Applications

WB

Protein ID

25009572

Physical Properties

Liquid

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