VCIP1 Antibody

Product Specifications

Background

VCIP1 acts as a deubiquitinating enzyme. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER) . Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP (By similarity) .

NCBI Gene ID

80124

Swiss Prot

Q96JH7

Accession Number

Q96JH7

Host

Rabbit

Reactivity

Human

Immunogen

This VCIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-151 amino acids from the N-terminal region of human VCIP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

134 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

VCPIP1

NCBI Official Name

Deubiquitinating protein VCIP135

NCBI Organism

Homo sapiens

Background Reference 01

Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (33) :12130-12135 (2004)

Background Reference 02

Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (33) :12130-12135 (2004)

Background Reference 03

Wang, Y., et al. J. Cell Biol. 164 (7) :973-978 (2004)

Background Reference 04

Ficarro, S., et al. J. Biol. Chem. 278 (13) :11579-11589 (2003)

Other Product Names

Deubiquitinating protein VCIP135, Valosin-containing protein p97/p47 complex-interacting protein 1, Valosin-containing protein p97/p47 complex-interacting protein p135, VCP/p47 complex-interacting 135-kDa protein, VCPIP1, KIAA1850, VCIP135