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Mouse Bmpr1b Antibody

Product Specifications

Background

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMPS/OP-1.

NCBI Gene ID

12167

Swiss Prot

P36898

Accession Number

P36898

Host

Rabbit

Reactivity

Human

Immunogen

This Mouse Bmpr1b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-160 amino acids from the Central region of mouse Bmpr1b.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-363

Calculated Molecular Weight

57 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Bmpr1b

NCBI Official Name

Bone morphogenetic protein receptor type-1B

NCBI Organism

Mus musculus

Background Reference 01

Chiang, P.M., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (37) :16320-16324 (2010)

Background Reference 02

Witte, F., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (32) :14211-14216 (2010)

Background Reference 03

Libusova, L., et al. Development 137 (14) :2297-2305 (2010)

Background Reference 04

Suzuki, Y., et al. J. Cell. Sci. 123 (PT 10), 1684-1692 (2010) :

Other Product Names

Bone morphogenetic protein receptor type-1B, BMP type-1B receptor, BMPR-1B, Activin receptor-like kinase 6, ALK-6, Serine/threonine-protein kinase receptor R6, SKR6, CDw293, Bmpr1b, Acvrlk6

Tested Applications

WB

Physical Properties

Liquid

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