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CC2D1A Antibody

Product Specifications

Background

CC2D1A is a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in nonsyndromic mental retardation-3.

NCBI Gene ID

54862

Swiss Prot

Q6P1N0

Accession Number

Q6P1N0

Host

Rabbit

Reactivity

Human

Immunogen

This CC2D1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the N-terminal region of human CC2D1A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-358

Calculated Molecular Weight

104 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CC2D1A

NCBI Official Name

Coiled-coil and C2 domain-containing protein 1A

NCBI Organism

Homo sapiens

Background Reference 01

Zhao, M., et al. J. Biol. Chem. 285 (32) :24372-24380 (2010)

Background Reference 02

Nakamura, A., et al. Biochem. Biophys. Res. Commun. 393 (4) :872-876 (2010)

Background Reference 03

Nakamura, A., et al. J. Cell Biol. 187 (5) :607-614 (2009)

Background Reference 04

McKay, G.J., et al. Invest. Ophthalmol. Vis. Sci. 50 (2) :533-539 (2009)

Other Product Names

Coiled-coil and C2 domain-containing protein 1A, Akt kinase-interacting protein 1, Five prime repressor element under dual repression-binding protein 1, FRE under dual repression-binding protein 1, Freud-1, Putative NF-kappa-B-activating protein 023N, CC2D1A, AKI1

Tested Applications

WB

Protein ID

74737148

Physical Properties

Liquid

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