GTF3C2 Antibody

Product Specifications

Background

GTF3C2 is required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1.

NCBI Gene ID

2976

Swiss Prot

Q8WUA4

Accession Number

Q8WUA4

Host

Rabbit

Reactivity

Human

Immunogen

This GTF3C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-170 amino acids from the N-terminal region of human GTF3C2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

101 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GTF3C2

NCBI Official Name

General transcription factor 3C polypeptide 2

NCBI Organism

Homo sapiens

Background Reference 01

Dumay-Odelot, H., et al. J. Biol. Chem. 282 (23) :17179-17189 (2007)

Background Reference 02

Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)

Background Reference 03

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 04

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Other Product Names

General transcription factor 3C polypeptide 2, TF3C-beta, Transcription factor IIIC 110 kDa subunit, TFIIIC 110 kDa subunit, TFIIIC110, Transcription factor IIIC subunit beta, GTF3C2, KIAA0011