CENPC1 Antibody

Product Specifications

Background

Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12. [provided by RefSeq].

NCBI Gene ID

1060

Swiss Prot

Q03188

Accession Number

Q03188

Host

Rabbit

Reactivity

Human

Immunogen

This CENPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-424 amino acids from the Central region of human CENPC1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

107 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CENPC

NCBI Official Name

Centromere protein C

NCBI Organism

Homo sapiens

Background Reference 01

Gopalakrishnan, S., et al. Hum. Mol. Genet. 18 (17) :3178-3193 (2009)

Background Reference 02

Yosifova, A., et al.Affect Disord 117 (1-2), 87-97 (2009) :

Background Reference 03

Baranzini, S.E., et al. Hum. Mol. Genet. 18 (4) :767-778 (2009)

Background Reference 04

Trazzi, S., et al. PLoS ONE (6), E5832 (2009) :

Other Product Names

Centromere protein C, CENP-C, Centromere autoantigen C, Centromere protein C 1, CENP-C 1, Interphase centromere complex protein 7, CENPC, CENPC1, ICEN7