LIM2 Antibody

Product Specifications

Background

LIM2 is an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation.

NCBI Gene ID

3982

Swiss Prot

P55344

Accession Number

P55344

Host

Rabbit

Reactivity

Human

Immunogen

This LIM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-137 amino acids from the C-terminal region of human LIM2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

20 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

LIM2

NCBI Official Name

Lens fiber membrane intrinsic protein

NCBI Organism

Homo sapiens

Background Reference 01

Ponnam, S.P., et al. Mol. Vis. 14, 1204-1208 (2008) :

Background Reference 02

Hsu, H., et al. Sheng Wu Gong Cheng Xue Bao 20 (4) :507-515 (2004)

Background Reference 03

Wistow, G., et al. Mol. Vis. 8, 171-184 (2002) :

Background Reference 04

Wistow, G., et al. Mol. Vis. 8, 185-195 (2002) :

Other Product Names

Lens fiber membrane intrinsic protein, MP18, MP19, MP20, LIM2

Tested Applications

Protein ID

17433717

Physical Properties

Liquid

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