NCOA4 Antibody

Product Specifications

Background

This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma.

NCBI Gene ID

8031

Swiss Prot

Q13772

Accession Number

Q13772

Host

Rabbit

Reactivity

Human

Immunogen

This NCOA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 496-524 amino acids from the C-terminal region of human NCOA4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

70 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NCOA4

NCBI Official Name

Nuclear receptor coactivator 4

NCBI Organism

Homo sapiens

Background Reference 01

Sadow, P.M., et al. Endocr. Pathol. 21 (2) :73-79 (2010)

Background Reference 02

Landa, I., et al. PLoS Genet. (9), E1000637 (2009) :

Background Reference 03

Richardson, D.S., et al. Cancer Res. 69 (11) :4861-4869 (2009)

Background Reference 04

Peng, Y., et al. Am. J. Pathol. 172 (1) :225-235 (2008)

Other Product Names

Nuclear receptor coactivator 4, NCoA-4, Androgen receptor coactivator 70 kDa protein, 70 kDa AR-activator, 70 kDa androgen receptor coactivator, Androgen receptor-associated protein of 70 kDa, Ret-activating protein ELE1, NCOA4, ARA70, ELE1, RFG