DNAH2 Antibody

Product Specifications

Background

Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH2 is an axonemal inner arm dynein heavy chain (Chapelin et al., 1997 [PubMed 9256245]) .

NCBI Gene ID

146754

Swiss Prot

Q9P225

Accession Number

Q9P225

Host

Rabbit

Reactivity

Human

Immunogen

This DNAH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-468 amino acids from the N-terminal region of human DNAH2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

508 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

DNAH2

NCBI Official Name

Dynein heavy chain 2, axonemal

NCBI Organism

Homo sapiens

Background Reference 01

Barrett, J.C., et al. Nat. Genet. (2009) In press :

Background Reference 02

Wistow, G., et al. Mol. Vis. 8, 196-204 (2002) :

Background Reference 03

Chapelin, C., et al. FEBS Lett. 412 (2) :325-330 (1997)

Other Product Names

Dynein heavy chain 2, axonemal, Axonemal beta dynein heavy chain 2, Ciliary dynein heavy chain 2, Dynein heavy chain domain-containing protein 3, DNAH2, DNAHC2, DNHD3, KIAA1503