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Mouse Cdk9 Antibody

Product Specifications

Background

Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II), SUPT5H and RDBP. The CDK9/cyclin-K complex has also a kinase activity toward CTD of RNAP II and can substitute for P-TEFb in vitro (By similarity) .

NCBI Gene ID

107951

Swiss Prot

Q99J95

Accession Number

Q99J95

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Mouse Cdk9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-278 amino acids from the C-terminal region of mouse Cdk9.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-303

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Cdk9

NCBI Official Name

Cyclin-dependent kinase 9

NCBI Organism

Mus musculus

Background Reference 01

Yokoyama, S., et al. Dev. Cell 17 (6) :836-848 (2009)

Background Reference 02

Alarcon, C., et al. Cell 139 (4) :757-769 (2009)

Background Reference 03

Takaya, T., et al. Circ. J. 73 (8) :1492-1497 (2009)

Background Reference 04

Kohoutek, J., et al. Mol. Cell. Biol. 29 (12) :3280-3285 (2009)

Other Product Names

Cyclin-dependent kinase 9, Cell division protein kinase 9, Cdk9

Tested Applications

WB

Physical Properties

Liquid

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