MAFA Antibody

Product Specifications

Background

MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS; MIM 176730) (Olbrot et al., 2002 [PubMed 12011435]) .

NCBI Gene ID

389692

Swiss Prot

Q8NHW3

Accession Number

Q8NHW3

Host

Rabbit

Reactivity

Human

Immunogen

This MAFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-315 amino acids from the C-terminal region of human MAFA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

37 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MAFA

NCBI Official Name

Transcription factor MafA

NCBI Organism

Homo sapiens

Background Reference 01

Lecoin, L., et al. Dev Neurobiol 70 (7) :485-497 (2010)

Background Reference 02

Guo, S., et al. J. Biol. Chem. 285 (17) :12655-12661 (2010)

Background Reference 03

Kondo, T., et al. Mol. Endocrinol. 23 (8) :1281-1290 (2009)

Background Reference 04

Kaneto, H., et al. Adv. Drug Deliv. Rev. 61 (7-8), 489-496 (2009) :

Other Product Names

Transcription factor MafA, Pancreatic beta-cell-specific transcriptional activator, Transcription factor RIPE3b1, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A, MAFA