CACNB1 Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.

NCBI Gene ID

782

Swiss Prot

Q02641

Accession Number

Q02641

Host

Rabbit

Reactivity

Human

Immunogen

This CACNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 543-572 amino acids from the C-terminal region of human CACNB1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

66 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CACNB1

NCBI Official Name

Voltage-dependent L-type calcium channel subunit beta-1

NCBI Organism

Homo sapiens

Background Reference 01

Jangsangthong, W., et al. Pflugers Arch. 459 (3) :399-411 (2010)

Background Reference 02

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 03

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 04

Lim, J., et al. Cell 125 (4) :801-814 (2006)

Other Product Names

Voltage-dependent L-type calcium channel subunit beta-1, CAB1, Calcium channel voltage-dependent subunit beta 1, CACNB1, CACNLB1

Tested Applications

Protein ID

20455481

Physical Properties

Liquid

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