LTB4R2 Antibody

Product Specifications

Background

Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.

NCBI Gene ID

56413

Swiss Prot

Q9NPC1

Accession Number

Q9NPC1

Host

Rabbit

Reactivity

Human

Immunogen

This LTB4R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 333-361 amino acids from the C-terminal region of human LTB4R2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Obesity, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

42 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

LTB4R2

NCBI Official Name

Leukotriene B4 receptor 2

NCBI Organism

Homo sapiens

Background Reference 01

Kim, G.Y., et al. J. Immunol. 184 (7) :3946-3954 (2010)

Background Reference 02

Ryu, H.C., et al. J. Invest. Dermatol. 130 (4) :1095-1106 (2010)

Background Reference 03

Choi, J.A., et al. Carcinogenesis 31 (4) :543-551 (2010)

Background Reference 04

Cho, K.J., et al. Am. J. Respir. Cell Mol. Biol. 42 (3) :294-303 (2010)

Other Product Names

Leukotriene B4 receptor 2, LTB4-R 2, LTB4-R2, LTB4 receptor JULF2, Leukotriene B4 receptor BLT2, Seven transmembrane receptor BLTR2, LTB4R2, BLT2R, BLTR2