NUDT2 Antibody
Product Specifications
Background
This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and three transcript variants, all encoding the same protein, have been identified.
NCBI Gene ID
318
Swiss Prot
P50583
Accession Number
P50583
Host
Rabbit
Reactivity
Human
Immunogen
This NUDT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-90 amino acids from the Central region of human NUDT2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=58-275
Calculated Molecular Weight
17 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NUDT2
NCBI Official Name
Bis (5'-nucleosyl) -tetraphosphatase [asymmetrical]
NCBI Organism
Homo sapiens
Background Reference 01
Vasilenko, N., et al. Virol. J. 7, 31 (2010) :
Background Reference 02
Swarbrick, J.D., et al. J. Biol. Chem. 280 (9) :8471-8481 (2005)
Background Reference 03
Swarbrick, J.D., et al. J. Biomol. NMR 31 (2) :181-182 (2005)
Background Reference 04
Pitcher, W.H. III, et al. Antiviral Res. 58 (3) :227-233 (2003)
Other Product Names
Bis (5'-nucleosyl) -tetraphosphatase [asymmetrical], Diadenosine 5',5'''-P1, P4-tetraphosphate asymmetrical hydrolase, Ap4A hydrolase, Ap4Aase, Diadenosine tetraphosphatase, Nucleoside diphosphate-linked moiety X motif 2, Nudix motif 2, NUDT2, APAH1
Tested Applications
WB
Physical Properties
Liquid
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