NUDT2 Antibody

This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and three transcript variants, all encoding the same protein, have been identified.

This NUDT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-90 amino acids from the Central region of human NUDT2.

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Bis (5'-nucleosyl) -tetraphosphatase [asymmetrical], Diadenosine 5',5'''-P1, P4-tetraphosphate asymmetrical hydrolase, Ap4A hydrolase, Ap4Aase, Diadenosine tetraphosphatase, Nucleoside diphosphate-linked moiety X motif 2, Nudix motif 2, NUDT2, APAH1