HCRTR1 Antibody

Product Specifications

Background

The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B.

NCBI Gene ID

3061

Swiss Prot

O43613

Accession Number

O43613

Host

Rabbit

Reactivity

Human

Immunogen

This HCRTR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-298 amino acids from the Central region of human HCRTR1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Neuroscience, Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HCRTR1

NCBI Official Name

Orexin receptor type 1

NCBI Organism

Homo sapiens

Background Reference 01

Peltonen, H.M., et al. Biochim. Biophys. Acta 1803 (10) :1206-1212 (2010)

Background Reference 02

Saus, E., et al.Psychiatr Res 44 (14) :971-978 (2010)

Background Reference 03

Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :

Background Reference 04

Turunen, P.M., et al. Br. J. Pharmacol. 159 (1) :212-221 (2010)

Other Product Names

Orexin receptor type 1, Ox-1-R, Ox1-R, Ox1R, Hypocretin receptor type 1, HCRTR1

Tested Applications

Physical Properties

Liquid

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