E2F7 Antibody
Product Specifications
Background
Along with E2F8, inhibitor of E2F-dependent transcription that is important for the control of the E2F1-TP53 apoptotic pathway. Directly represses E2F1 transcription (By similarity) . Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession.
NCBI Gene ID
144455
Swiss Prot
Q96AV8
Accession Number
Q96AV8
Host
Rabbit
Reactivity
Human
Immunogen
This E2F7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 591-619 amino acids from the Central region of human E2F7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=58-268
Calculated Molecular Weight
100 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
E2F7
NCBI Official Name
Transcription factor E2F7
NCBI Organism
Homo sapiens
Other Product Names
Transcription factor E2F7, E2F-7, E2F7
Tested Applications
WB
Protein ID
311033456
Physical Properties
Liquid
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